Supercharging

The Immune System


NKore is combining a natural, proprietary approach to “Supercharging” allogeneic Natural Killer Cells to deploy a new era in immunotherapeutic medicine for the treatment of cancer, and other immune-related diseases, in patients of all ages. At NKore, we put patients first!



NK101
Backed by Over 25 Years of
Research, Our Allogeneic sNK
Therapy, NK101, Offers a Non-Toxic
Approach to Cancer Healthcare
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Patient Stories
From Adults to Pediatrics,
NK101 is Showing Promise in
Both Solid and Blood Cancers
Without the Harsh Side Effects.
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Path to Market
Focused on FDA Approval
in the United States, NKore
is Positioned to Begin Human
Trials in 2025
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NKore BioTherapeutics is a cellular-based biotherapeutics company focused on the early detection, prevention, and treatment of cancer. Our technology is based on a proprietary method of activating natural killer (NK) cells, creating Supercharged Natural Killer (sNK) cells used as a novel oncology immunotherapy platform. Our proprietary activation method enhances NK cells’ overall effectiveness, making them significantly more potent (i.e., they are more cytotoxic to the cancer cells), while reducing the likelihood of tumor regeneration and metastasis.

The technology was developed by Dr. Anahid Jewett, the Company’s co-founder and Chief Scientific Advisor. Based on positive preclinical results, we believe that Dr. Jewett’s 30-plus years of researching NK cell function has resulted in the development of a novel and effective cancer immunotherapy. NKore’s current focus is to translate and replicate the positive preclinical results into human clinical trials and achieve marketing approval. Patients are actively receiving treatments and showing early signs of a positive response with no negative side effects currently reported.

Backed by over 25 years of research, our proprietary supercharging process, using allogeneic natural killer cells from healthy adults, makes our NK cells more cytotoxic and more robust in the tumor microenvironment. Meaning, they kill more aggressively and last longer. Pioneered by Dr. Anahid Jewett at UCLA, NKore is developing the next generation in cell therapies using a non-toxic approach.

Scientific Foundation

News & Events

Latest & Greatest

By Tracy Ryan June 20, 2025
At this year’s Innate Killer Summit in San Diego , one of the most powerful and lasting impressions came from the work and wisdom of our beloved scientific founder, Dr. Anahid Jewett . Dr. Jewett, a pioneering immunologist and globally recognized NK cell expert, gave what would become some of her final public presentations—leaving an unforgettable mark on the international community of innate immune researchers and biotech leaders. Her talks, delivered with characteristic brilliance and humility, distilled decades of research into a clear, compelling vision: that natural killer cells are the future of cancer therapy , and that future is already within reach. Her presentations spanned the arc of her life’s work—from her early discoveries in NK cell cytotoxicity and tumor immune evasion, to the breakthrough techniques she developed to “supercharge” NK cells for clinical use. She walked the audience through the translational path from lab bench to bedside, showing data from patient studies that support the promise of non-toxic, precision immunotherapy for some of the most treatment-resistant cancers. But what made her presence at BPI’s Innate Killer Summit so deeply moving was not just the science—it was her spirit. Her commitment to patients, her fierce intellect, and her belief in the power of immune-based healing came through in every word. The response from the audience was overwhelming. Researchers, physicians, and investors alike approached our team throughout the week to express their gratitude for her work and their admiration for her clarity of vision. One attendee called her “the North Star of NK cell science.” We couldn’t agree more. As a company, NKore BioTherapeutics has been built on the foundation of Dr. Jewett’s groundbreaking research. And though she is no longer with us physically, she has left behind something far more powerful: a blueprint for innovation, a roadmap for clinical success, and an unshakable commitment to saving lives . We are proud to carry forward her legacy. We are advancing the very therapies she envisioned, treating patients who once had no options, and moving closer every day to an era where cancer can be treated effectively and gently—through the body’s own immune defenses. Thank you, Dr. Jewett, for everything. You’ve given the world more than it knows, and we will never stop building the future you helped us see.
March 21, 2025
At this year’s BioProcess International U.S. West (BPI West) conference in San Diego, Tracy Ryan , Co-Founder and Chief Communications Officer of NKore BioTherapeutics , delivered a powerful plenary keynote that resonated deeply with attendees. The keynote wove together a deeply personal origin story with a compelling scientific roadmap for NKore’s flagship therapy, NK101 , an off-the-shelf natural killer (NK) cell immunotherapy platform. From Personal Tragedy to Scientific Breakthrough Ryan opened her address with the emotional account of her daughter Sophie’s diagnosis with a brain tumor at just eight and a half months old. This life-altering event became the catalyst for founding NKore, in collaboration with Dr. Anahid Jewett of UCLA, with the goal of advancing safer, more effective immunotherapies—especially for children facing aggressive cancers. NK101: A Next-Generation NK Cell Therapy During the keynote, Ryan introduced NK101 , NKore’s allogeneic NK cell product designed to be potent, non-toxic, and ready-to-use. The company’s preclinical data show promising safety and efficacy, and NK101 is on track to enter U.S. clinical trials in 2026. The announcement generated enthusiastic feedback from investors, scientists, and biopharma leaders alike, signaling strong momentum for NKore’s platform. Reflections from the Conference Floor Ryan’s presentation aligned closely with BPI West’s broader themes around innovation in advanced biologics manufacturing. Industry leaders like Amy Shaw of Takeda emphasized the importance of early-stage design and scalable automation for cell therapy manufacturing—principles that NKore has embraced from the outset. Other conference highlights included forward-looking panels on AI-driven optimization , digital twin technology , and the industrialization of allogeneic platforms , underscoring the sector’s commitment to turning complex cell therapies into reproducible, commercial-grade products. A Vision for the Future The energy at BPI West 2025 reflected a pivotal moment in NK cell therapy development. NKore BioTherapeutics is now moving from vision to validation, bringing NK101 to the clinic in pursuit of safe, non-toxic, and scalable solutions for cancer patients. Learn More Bioprocess Online featured coverage of the event, including insights from Ryan’s keynote. Read the full article here. 
By Tracy Ryan March 5, 2025
At this year’s Innate Killer Summit in San Diego , one moment stood out among the many brilliant talks and groundbreaking discoveries—a plenary keynote that brought the room to its feet not once, but twice . That keynote was ours. Sharing the stage with my daughter—who has battled brain cancer her entire life—was one of the most profound honors of my life. Together, we shared not just a personal journey through the darkest days of pediatric cancer, but a story of scientific resolve, patient courage, and the incredible promise of NK (natural killer) cell therapy. Our presentation, which opened Day 2 of the Summit, chronicled the birth of NKore BioTherapeutics , the company we founded to develop non-toxic, supercharged NK cell therapies for cancer and immune-related diseases. We spoke candidly about the devastating diagnosis my daughter received at just 8 1/2 months old, the years of failed treatments, and the ultimate turning point—an experimental NK cell infusion that marked a turning point in her recovery. The room was silent as we walked through the science: how our NK cells are engineered to work smarter, last longer, and target tumors without harming healthy tissue. But what made the biggest impact wasn’t just the data—it was my daughter walking on stage herself, full of life and spirit, to share her voice. The first standing ovation came after her speech. The second came at the end, when we declared our mission loud and clear: We will not stop until every patient has access to the same kind of hope. We left the stage overwhelmed with emotion, gratitude, and even greater resolve. The support we received from leading researchers, clinicians, and investors reminded us that the tide is turning in cancer care. The future isn’t just coming—it’s already being built, and it’s being built by people who believe that the immune system, when properly supported, can do what once seemed impossible. Thank you to the organizers of the Innate Killer Summit , to the community that welcomed our story, and to every patient and family who continues to inspire our work. This was more than a keynote. It was a call to action. We heard you. And we’re just getting started.
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Documentary Teaser Trailer

Saving Sophie: The Road to a Cure



In this 9-minute teaser to the poignant documentary "Saving Sophie: The Road to a Cure," you are invited into the heart-wrenching journey of the Ryan family, who faced the unimaginable when their daughter Sophie was diagnosed with a brain tumor at just 8½ months old. This film gives an inside look at their relentless fight for her life and the incredible resilience of a mother who, in the face of adversity, CoFounded NKore BioTherapeutics with world renowned research scientist, and UCLA professor and director of the tumor immunology board, Dr. Anahid Jewett. 


NKore is revolutionizing cancer treatment and offering hope to countless families. Witness the power of love, innovation, and determination in a story that will inspire and uplift, as the NKore team strives not only to save Sophie, but to transform the future of cancer care.

Review Patient Stories